Kandinsky™ Survival Regulation
Progenitor Kandinsky™ Survival Regulation produces cells that require treatment with biologically and medically safe small molecules to maintain proliferation. For industrial applications, cell proliferation and survival can be controlled via specific additives in the media in which cells are maintained. For therapeutic applications, in vivo cell growth and proliferation and survival can be controlled by treatment of patients with medically safe, well-characterized, and well-tolerated compounds, enabling unprecedented control over induction, maintenance, and relapse phases of cell-based therapies. A unique feature of Kandinsky™ is that it employs an all-or-nothing regulation element that prevents genetic drift and development of resistance.