Van Gogh™ Footprint-Free Gene Editing

VanGogh-Illustration-Smaller-Web

Product Description

Progenitor Progenitor’s Van GoghTM Footprint-Free Gene Editing technology improves nuclease-based genetic engineering of immune cells by developing an efficient approach for removing unwanted selection cassette DNA. Van GoghTM Footprint-Free Gene Editing is a novel ‘self-excising’ cassette that enables rapid, permanent removal of the selection cassette by brief treatment of cells with a small molecule that induces Cre/loxP-mediated DNA recombination without possible reinsertion of deleted elements found in current gene editing market techniques. This technology ensures new levels of safety in constructs for cell immunotherapy.